The exponential growth of APIs, further accelerated by IoT, micro-services, and FaaS, brought many challenges, both technical and economical. On the one hand, businesses are struggling with establishing successful API programs to connect with their customers. On the other side, engineering teams are facing out-of-the-scale complexity. In this talk, we will explore the problems and shortcomings of current APIs, both with regards to the technical aspects and the API economy. We will discuss the possible solutions to these problems and introduce Autonomous APIs. In the second part, we will take a look at what are Autonomous APIs and how they can solve the problems for both businesses and engineering. We will introduce the classification of autonomous systems and take a peek at the building blocks of autonomous systems.